The UEFA Champions League knockout stage kicks off tonight with four Round of 16 first-leg matches. All of the following matches will kick off at 10pm, except for Club Brugge’s clash with Aston Villa, which kicks off at 7:45pm.

Madrid Derby: Real Madrid against Atletico Madrid will be meeting on the pitch of Santiago Bernabéu tonight. Los Blancos secured their spot after eliminating Manchester City in the playoff round, while the Colchoneros qualified by finishing fifth in the league stage. These two teams have faced each other twice before for the Champions League final in 2014 and 2016, with Real Madrid hoisting the trophy both times.

Arsenal heads to face PSV Eindhoven. The Dutch earned their spot after knocking out Juventus in the playoffs, while Arsenal finished third in the league stage. These two teams have faced each other eight times before, with Arsenal clinching three matches, PSV winning one, and four ending in a draw.

Borussia Dortmund hosts Lille at Signal Iduna Park. Lille secured direct qualification by finishing seventh in the league stage, while Dortmund reached the Round of 16 after defeating Sporting Lisbon in the playoffs.

On our home turf: Zamalek’s last match in the Egyptian Premier League’s first phase will be taking place tonight at 9pm. Zamalek will visit Enppi in the 17th round of the Egyptian Premier League with hopes to reclaim their third place spot, which Al Masry snatched yesterday. This also marks Zamalek’s first match under their new head coach Jose Peseiro.

Al Ittihad will be facing Smouha in the Alexandria Derby, while Ismaily travels to face ZED — both matches also kick off at 9 pm.